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15 ml bottle
ACI Pharmaceuticals LtdProduct Description
Indications
• Respiratory Tract Infections: Lower respiratory tract infections (bronchitis, pneumonia) and upper respiratory tract infections (sinusitis, pharyngitis, tonsillitis).
• Other Infections: Otitis media (middle ear infection), skin and soft tissue infections, and typhoid fever.
• Sexually Transmitted Diseases (STDs): Non-gonococcal urethritis and cervicitis caused by Chlamydia trachomatis.
Dosage & Administration
• Adults (Oral): 500 mg once daily for 3 days; OR 500 mg on Day 1, followed by 250 mg once daily on Days 2–5.
• STDs (Chlamydia): 1 g as a single dose (or 500 mg on Day 1, then 250 mg daily for 2 days).
• Typhoid Fever: 500 mg once daily for 7–10 days.
• Children (Oral Suspension): 10 mg/kg once daily for 3 days.
o 15–25 kg: 200 mg (1 teaspoonful) daily for 3 days.
o 26–35 kg: 300 mg (1.5 teaspoonfuls) daily for 3 days.
o 36–45 kg: 400 mg (2 teaspoonfuls) daily for 3 days.
• Administration: Take at least 1 hour before or 2 hours after a meal. Reconstitute suspension powder with boiled and cooled water up to the mark and shake well before use.
Side Effects
• Mostly mild-to-moderate gastrointestinal symptoms: Nausea, vomiting, abdominal pain/cramps, diarrhea, loose stools, and flatulence.
• Allergic reactions (skin rash, photosensitivity, rarely severe hypersensitivity/anaphylaxis).
• Reversible elevation in liver transaminases, rare cases of cholestatic jaundice, and temporary hearing impairment with prolonged high doses.
Drug Interactions
• Antacids: Take Azithromycin at least 1 hour before or 2 hours after antacids.
• Ergot Derivatives: Co-administration is contraindicated due to the risk of ergotism.
• Digoxin, Cyclosporin, & Warfarin: Require caution and proper monitoring of drug levels/prothrombin time when used concurrently.
Contraindications & Precautions
• Contraindications: Hypersensitivity to azithromycin or any macrolide antibiotic, hepatic (liver) diseases, and co-administration with ergot derivatives.
• Precautions: Use with caution in patients with severe renal (kidney) impairment. Discontinue immediately if severe allergic reactions (e.g., angioedema, anaphylaxis) occur.
Pregnancy & Lactation
• Pregnancy Category B: Should be used during pregnancy only if adequate alternatives are not available.
• Lactation: Caution should be exercised as it is not known whether azithromycin is secreted in human breast milk.
Quick Tips
• Complete the Full Course: Do not stop early even if you feel better to prevent antibiotic resistance and recurrence.
• Food & Antacids: Maintain a 1-hour before or 2-hour after gap with food and antacids.
• Medical Advice: Always take this medication under the supervision of a registered doctor.
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