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Square Pharmaceuticals PLCProduct Description
Flugal, which contains fluconazole, is a potent antifungal medication belonging to the triazole class, primarily utilized to treat a wide range of yeast and fungal infections, including candidiasis and cryptococcal meningitis. It functions by inhibiting the fungal enzyme 14alpha-demethylase, which disrupts the synthesis of ergosterol, a critical component of the fungal cell membrane; this disruption compromises the membrane's integrity and halts the growth of the pathogen. Highly regarded for its excellent oral bioavailability and ability to penetrate most body fluids, fluconazole is available in both oral and intravenous formulations. Its long half-life often allows for convenient single-dose treatments for uncomplicated infections, though its tendency to interact with various cytochrome P450 liver enzymes requires careful clinical monitoring when co-administered with other medications.
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