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1 Strip = 10 Tablets
Servier Bangladesh OperationProduct Description
Diosmin + Hesperidin is a widely utilized micronized purified flavonoid fraction (MPFF) combination that serves as a cornerstone in the pharmacological management of chronic venous insufficiency (CVI) and hemorrhoidal disease. This synergistic pairing acts as a potent phlebotonic and vascular protector by enhancing venous tone, improving lymphatic drainage, and protecting the microcirculation from inflammatory damage. The primary mechanism involves prolonging the vasoconstrictor effect of norepinephrine on the venous wall, which increases venous capacitance and reduces venous distensibility and stasis. Furthermore, this combination inhibits the activation and adhesion of leukocytes to the capillary endothelium, thereby reducing capillary permeability and preventing the release of inflammatory mediators that lead to edema and tissue damage. Clinically, it is highly effective in alleviating symptoms such as heavy legs, pain, nocturnal cramps, and swelling associated with varicose veins, as well as providing rapid relief from pain and bleeding during acute hemorrhoidal attacks. Its micronized form is particularly significant, as it significantly enhances gastrointestinal absorption and bioavailability compared to non-micronized flavonoids, ensuring a more consistent therapeutic response.
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