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1 Strip = 6 Tablets
Incepta Pharmaceuticals Ltd.Product Description
Sitagil M contains the fixed-dose combination of Sitagliptin and Metformin Hydrochloride, a combination oral antihyperglycemic medication used primarily to improve glycemic control in adults with type 2 diabetes mellitus. This formulation utilizes two distinct mechanisms of action: Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, works by increasing the levels of incretin hormones, which stimulate insulin release and decrease glucagon production in a glucose-dependent manner. Metformin, a biguanide, complements this by improving insulin sensitivity, increasing peripheral glucose uptake, and reducing hepatic glucose production. When used alongside diet and exercise, this synergistic approach effectively lowers both fasting and postprandial plasma glucose levels while carrying a lower risk of hypoglycemia compared to sulfonylureas. Common side effects often include gastrointestinal upset, such as nausea or diarrhea, which are typically attributed to the metformin component and can often be managed by taking the medication with meals.
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