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1 Strip = 10 Tablets
Incepta Pharmaceuticals Ltd.Product Description
The combination of Clopidogrel and Aspirin, often referred to as Dual Antiplatelet Therapy (DAPT), is a pharmacological cornerstone in preventing atherothrombotic events. These two agents exert a synergistic effect by inhibiting platelet aggregation through distinct pathways: Aspirin irreversibly inhibits the cyclooxygenase-1 (COX-1) enzyme to prevent the formation of thromboxane A2, while Clopidogrel is a prodrug that binds to the P2Y12 receptor, blocking adenosine diphosphate (ADP)-induced platelet activation. This dual inhibition significantly reduces the risk of myocardial infarction, stroke, and stent thrombosis in patients with acute coronary syndrome (ACS) or those undergoing percutaneous coronary intervention (PCI). While highly effective in maintaining vascular patency, the combination carries an increased risk of gastrointestinal bleeding and bruising, requiring careful clinical monitoring of the patient's hematological profile.
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