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1 Strip = 14 Tablets
Opsonin Pharma LtdProduct Description
Calnor contains the fixed-dose combination of Amlodipine and Olmesartan Medoxomil, a potent antihypertensive treatment that employs a dual-pathway approach to achieve effective blood pressure control. Amlodipine functions as a dihydropyridine calcium channel blocker that induces peripheral vasodilation by preventing calcium ions from entering vascular smooth muscle cells, thereby lowering systemic resistance. Complementing this, Olmesartan Medoxomil is a long-acting angiotensin II receptor blocker (ARB) that inhibits the renin-angiotensin-aldosterone system (RAAS) by blocking the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This synergistic pairing allows for a more comprehensive reduction in blood pressure than either agent used alone and is particularly indicated for patients who require multiple medications to reach their target levels. Clinically, the addition of an ARB like olmesartan can help mitigate the peripheral edema often associated with amlodipine monotherapy, though patients should still be monitored for potential side effects such as dizziness, hypotension, and hyperkalemia.
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