Product Description

Indications: Becoral DX is indicated for the treatment and prevention of osteoporosis, osteomalacia, tetany, hypoparathyroidism, and disorders of osteogenesis. It is also used as a calcium supplement in childhood nutritional deficiency, rickets, pregnancy, lactation, elderly patients, chronic renal failure, pancreatitis, and other conditions associated with calcium deficiency.

Composition: Each DX tablet contains Calcium Carbonate USP 1500 mg (coral source) equivalent to 600 mg elemental calcium and Vitamin D3 400 IU.

Pharmacology: Calcium is essential for maintaining healthy bones, teeth, muscle function, and normal biochemical processes. Vitamin D3 enhances calcium absorption from the gastrointestinal tract and helps maintain calcium balance in the body. The coral-derived calcium used in Becoral DX has a structure similar to human bone, which may support better absorption and utilization. Combined calcium and vitamin D supplementation helps improve bone density and reduce the risk of osteoporosis and fractures.

Dosage & Administration: Usually one tablet once or twice daily with plenty of water, preferably after meals for better absorption, or as directed by the physician. Effervescent tablets should be dissolved in a glass of water before administration.

Interaction: Thiazide diuretics may increase calcium levels and require monitoring. Corticosteroids can reduce calcium absorption. Calcium may interfere with absorption of tetracyclines, bisphosphonates, sodium fluoride, iron, and certain other medications, so appropriate time gaps should be maintained. Foods rich in oxalic acid or phytic acid may decrease calcium absorption. Concomitant use with cardiac glycosides requires caution because hypercalcemia may increase toxicity risk.

Contraindications: Contraindicated in hypercalcemia, hypercalciuria, nephrolithiasis, severe renal insufficiency, hyperparathyroidism, hypersensitivity to any ingredient, and patients receiving digoxin therapy without proper monitoring.

Side Effects: May cause constipation, gastrointestinal irritation, nausea, vomiting, dry mouth, decreased appetite, drowsiness, allergic reactions, or irregular heartbeat. Excessive intake may lead to hypercalcemia.

Pregnancy & Lactation: Can be used during pregnancy and breastfeeding when calcium and vitamin D deficiency exists, but excessive intake should be avoided. Daily intake during pregnancy should not exceed recommended limits. Calcium and vitamin D pass into breast milk.

Precautions & Warnings: Long-term use requires monitoring of serum calcium and renal function, especially in elderly patients and those taking diuretics or cardiac glycosides. Use cautiously in renal impairment, sarcoidosis, immobilized osteoporosis patients, and those at risk of kidney stones. Additional vitamin D or calcium supplementation should only be taken under medical supervision.

Overdose Effects: Overdose may result in hypercalcemia and hypervitaminosis D. Symptoms may include nausea, vomiting, constipation, abdominal pain, thirst, weakness, confusion, excessive urination, kidney stones, arrhythmias, and severe renal complications. Severe toxicity may require hospitalization and supportive treatment.

Therapeutic Class: Specific mineral and vitamin combined preparation

Storage Conditions: Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.