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Square Pharmaceuticals PLCProduct Description
Diclofenac Sodium is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the phenylacetic acid derivative group, widely prescribed for the management of acute and chronic pain, inflammation, and swelling associated with conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It functions primarily by inhibiting the cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of pro-inflammatory prostaglandins. As a sodium salt, it is characterized by relatively rapid absorption, and it is available in various dosage forms, including tablets, gels, and injectables. While highly effective as an analgesic and antipyretic, its use must be balanced against potential risks, particularly gastrointestinal irritation, renal impairment, and an increased risk of cardiovascular events with long-term, high-dose administration. Due to its potent activity, it is often formulated as enteric-coated or sustained-release tablets to mitigate direct gastric mucosal damage.
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